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Identification of Morphine and Heroin-Treatment in Mice Using Metabonomics

Although heroin and morphine are structural analogues and morphine is a metabolite of heroin, it is not known how the effect of each substance on metabolites in vivo differs. Heroin and morphine were administered to C57BL/6J mice in increasing doses from 2 to 25 and 3 to 9 mg kg(−1) (twice a day, i....

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Detalles Bibliográficos
Autores principales: Lu, Wuhuan, Zhang, Ran, Sheng, Wei, Feng, Luohua, Xu, Peng, Wang, Youmei, Xie, Yuan, Xu, Hui, Wang, Guangji, Aa, Jiye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467231/
https://www.ncbi.nlm.nih.gov/pubmed/34564423
http://dx.doi.org/10.3390/metabo11090607