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Identification of Morphine and Heroin-Treatment in Mice Using Metabonomics
Although heroin and morphine are structural analogues and morphine is a metabolite of heroin, it is not known how the effect of each substance on metabolites in vivo differs. Heroin and morphine were administered to C57BL/6J mice in increasing doses from 2 to 25 and 3 to 9 mg kg(−1) (twice a day, i....
Autores principales: | Lu, Wuhuan, Zhang, Ran, Sheng, Wei, Feng, Luohua, Xu, Peng, Wang, Youmei, Xie, Yuan, Xu, Hui, Wang, Guangji, Aa, Jiye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467231/ https://www.ncbi.nlm.nih.gov/pubmed/34564423 http://dx.doi.org/10.3390/metabo11090607 |
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