Synthesis of 6-Membered-Ring Fused Thiazine-Dicarboxylates and Thiazole-Pyrimidines via One-Pot Three-Component Reactions

A facile and efficient one-pot three-component reaction method for the synthesis of thiazine-dicarboxylates is reported. Reaction of an isocyanide and dialkyl acetylenedicarboxylate with 2-amino-4H-1,3-thiazin-4-one derivatives containing both an acidic proton and an internal nucleophile gave the pr...

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Detalles Bibliográficos
Autores principales: Mohlala, Reagan L., Coyanis, Elena Mabel, Fish, Muhammad Q., Fernandes, Manuel A., Bode, Moira L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467237/
https://www.ncbi.nlm.nih.gov/pubmed/34576965
http://dx.doi.org/10.3390/molecules26185493