Integrative genomics analysis of nasal intestinal-type adenocarcinomas demonstrates the major role of CACNA1C and paves the way for a simple diagnostic tool in male woodworkers

BACKGROUND: Nasal intestinal-type adenocarcinomas (ITAC) are strongly related to chronic wood dust exposure: The intestinal phenotype relies on CDX2 overexpression but underlying molecular mechanisms remain unknown. Our objectives were to investigate transcriptomic and methylation differences betwee...

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Detalles Bibliográficos
Autores principales: Gallet, Patrice, Oussalah, Abderrahim, Pouget, Celso, Dittmar, Gunnar, Chery, Celine, Gauchotte, Guillaume, Jankowski, Roger, Gueant, Jean Louis, Houlgatte, Rémi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467244/
https://www.ncbi.nlm.nih.gov/pubmed/34563241
http://dx.doi.org/10.1186/s13148-021-01122-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467244/
https://www.ncbi.nlm.nih.gov/pubmed/34563241
http://dx.doi.org/10.1186/s13148-021-01122-5

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