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CBP/p300 Bromodomain Inhibitor–I–CBP112 Declines Transcription of the Key ABC Transporters and Sensitizes Cancer Cells to Chemotherapy Drugs

SIMPLE SUMMARY: Despite tremendous advances in cancer treatment, chemotherapy remains the first-line choice in many tumor types. The action of numerous chemotherapy drugs is limited by the occurrence of ABC proteins in cancer cell membranes, which remove medicines from cell compartments. In this pap...

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Detalles Bibliográficos
Autores principales: Strachowska, Magdalena, Gronkowska, Karolina, Michlewska, Sylwia, Robaszkiewicz, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467251/
https://www.ncbi.nlm.nih.gov/pubmed/34572840
http://dx.doi.org/10.3390/cancers13184614