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Roles and Mechanisms of Deubiquitinases (DUBs) in Breast Cancer Progression and Targeted Drug Discovery

Deubiquitinase (DUB) is an essential component in the ubiquitin—proteasome system (UPS) by removing ubiquitin chains from substrates, thus modulating the expression, activity, and localization of many proteins that contribute to tumor development and progression. DUBs have emerged as promising progn...

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Detalles Bibliográficos
Autores principales: Li, Sixuan, Zhang, Hongquan, Wei, Xiaofan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467271/
https://www.ncbi.nlm.nih.gov/pubmed/34575114
http://dx.doi.org/10.3390/life11090965