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Role of Ezrin/Radixin/Moesin in the Surface Localization of Programmed Cell Death Ligand-1 in Human Colon Adenocarcinoma LS180 Cells

Programmed cell death ligand-1 (PD-L1), an immune checkpoint protein highly expressed on the cell surface in various cancer cell types, binds to programmed cell death-1 (PD-1), leading to T-cell dysfunction and tumor survival. Despite clinical successes of PD-1/PD-L1 blockade therapies, patients wit...

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Detalles Bibliográficos
Autores principales: Kobori, Takuro, Tanaka, Chihiro, Tameishi, Mayuka, Urashima, Yoko, Ito, Takuya, Obata, Tokio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467328/
https://www.ncbi.nlm.nih.gov/pubmed/34577564
http://dx.doi.org/10.3390/ph14090864