Effects of SLCO1B1 and SLCO1B3 Genetic Polymorphisms on Valsartan Pharmacokinetics in Healthy Korean Volunteers

Purpose: This study aimed to examine OATP1B1 (SLCO1B1) and OATP1B3 (SLCO1B3) on the pharmacokinetics of valsartan. Twenty-five subjects were genotyped for 16 single-nucleotide polymorphisms of the SLCO1B1 and SLCO1B3 genes. Methods: After a single dose of 160 mg of valsartan was orally administered...

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Detalles Bibliográficos
Autores principales: Song, Gonjin, Chung, Jee-Eun, Yee, Jeong, Lee, Kyung-Eun, Park, Kyungsoo, Gwak, Hye-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467379/
https://www.ncbi.nlm.nih.gov/pubmed/34575639
http://dx.doi.org/10.3390/jpm11090862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467379/
https://www.ncbi.nlm.nih.gov/pubmed/34575639
http://dx.doi.org/10.3390/jpm11090862

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