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SIRT7 Acts as a Guardian of Cellular Integrity by Controlling Nucleolar and Extra-Nucleolar Functions

Sirtuins are key players for maintaining cellular homeostasis and are often deregulated in different human diseases. SIRT7 is the only member of mammalian sirtuins that principally resides in the nucleolus, a nuclear compartment involved in ribosomal biogenesis, senescence, and cellular stress respo...

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Detalles Bibliográficos
Autores principales: Kumari, Poonam, Tarighi, Shahriar, Braun, Thomas, Ianni, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467518/
https://www.ncbi.nlm.nih.gov/pubmed/34573343
http://dx.doi.org/10.3390/genes12091361