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Selective Targeting of Human and Animal Pathogens of the Helicobacter Genus by Flavodoxin Inhibitors: Efficacy, Synergy, Resistance and Mechanistic Studies

Antimicrobial resistant (AMR) bacteria constitute a global health concern. Helicobacter pylori is a Gram-negative bacterium that infects about half of the human population and is a major cause of peptic ulcer disease and gastric cancer. Increasing resistance to triple and quadruple H. pylori eradica...

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Detalles Bibliográficos
Autores principales: Salillas, Sandra, Galano-Frutos, Juan José, Mahía, Alejandro, Maity, Ritwik, Conde-Giménez, María, Anoz-Carbonell, Ernesto, Berlamont, Helena, Velazquez-Campoy, Adrian, Touati, Eliette, Mamat, Uwe, Schaible, Ulrich E., Gálvez, José A., Díaz-de-Villegas, María D., Haesebrouck, Freddy, Aínsa, José A., Sancho, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467567/
https://www.ncbi.nlm.nih.gov/pubmed/34576300
http://dx.doi.org/10.3390/ijms221810137