The Short-Chain Fatty Acid Butyrate Attenuates Pulmonary Vascular Remodeling and Inflammation in Hypoxia-Induced Pulmonary Hypertension

Pulmonary hypertension (PH) is a progressive cardiovascular disorder in which local vascular inflammation leads to increased pulmonary vascular remodeling and ultimately to right heart failure. The HDAC inhibitor butyrate, a product of microbial fermentation, is protective in inflammatory intestinal...

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Detalles Bibliográficos
Autores principales: Karoor, Vijaya, Strassheim, Derek, Sullivan, Timothy, Verin, Alexander, Umapathy, Nagavedi S., Dempsey, Edward C., Frank, Daniel N., Stenmark, Kurt R., Gerasimovskaya, Evgenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467617/
https://www.ncbi.nlm.nih.gov/pubmed/34576081
http://dx.doi.org/10.3390/ijms22189916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467617/
https://www.ncbi.nlm.nih.gov/pubmed/34576081
http://dx.doi.org/10.3390/ijms22189916

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