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The Short-Chain Fatty Acid Butyrate Attenuates Pulmonary Vascular Remodeling and Inflammation in Hypoxia-Induced Pulmonary Hypertension
Pulmonary hypertension (PH) is a progressive cardiovascular disorder in which local vascular inflammation leads to increased pulmonary vascular remodeling and ultimately to right heart failure. The HDAC inhibitor butyrate, a product of microbial fermentation, is protective in inflammatory intestinal...
Autores principales: | Karoor, Vijaya, Strassheim, Derek, Sullivan, Timothy, Verin, Alexander, Umapathy, Nagavedi S., Dempsey, Edward C., Frank, Daniel N., Stenmark, Kurt R., Gerasimovskaya, Evgenia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467617/ https://www.ncbi.nlm.nih.gov/pubmed/34576081 http://dx.doi.org/10.3390/ijms22189916 |
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