Identification of Small Molecule Inhibitors against Staphylococcus aureus Dihydroorotase via HTS

Drug-resistant Staphylococcus aureus is an imminent threat to public health, increasing the importance of drug discovery utilizing unexplored bacterial pathways and enzyme targets. De novo pyrimidine biosynthesis is a specialized, highly conserved pathway implicated in both the survival and virulenc...

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Detalles Bibliográficos
Autores principales: Rice, Amy J., Pesavento, Russell P., Ren, Jinhong, Youn, Isoo, Kwon, Youngjin, Ellepola, Kassapa, Che, Chun-Tao, Johnson, Michael E., Lee, Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467647/
https://www.ncbi.nlm.nih.gov/pubmed/34576147
http://dx.doi.org/10.3390/ijms22189984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467647/
https://www.ncbi.nlm.nih.gov/pubmed/34576147
http://dx.doi.org/10.3390/ijms22189984

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