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The AST-120 Recovers Uremic Toxin-Induced Cognitive Deficit via NLRP3 Inflammasome Pathway in Astrocytes and Microglia

Chronic kidney disease (CKD) is characterized by the progressive loss of renal function; moreover, CKD progression commonly leads to multiple comorbidities, including neurological dysfunction and immune disorders. CKD-triggered neuroinflammation significantly contributes to cognitive impairment. Thi...

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Detalles Bibliográficos
Autores principales: Li, Lung-Chih, Chen, Wei-Yu, Chen, Jin-Bor, Lee, Wen-Chin, Chang, Chiung-Chih, Tzeng, Hong-Tai, Huang, Chiang-Chi, Chang, Ya-Jen, Yang, Jenq-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467651/
https://www.ncbi.nlm.nih.gov/pubmed/34572437
http://dx.doi.org/10.3390/biomedicines9091252