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Impairment of the Hypothalamus–Pituitary–Thyroid Axis Caused by Naturally Occurring GATA2 Mutations In Vitro

The transcription factor GATA2 regulates gene expression in several cells and tissues, including hematopoietic tissues and the central nervous system. Recent studies revealed that loss-of-function mutations in GATA2 are associated with hematological disorders. Our earlier in vitro studies showed tha...

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Detalles Bibliográficos
Autores principales: Sakai, Yuki, Ohba, Kenji, Sasaki, Shigekazu, Matsushita, Akio, Nakamura, Hiroko Misawa, Kuroda, Go, Tsuriya, Daisuke, Yamashita, Miho, Suda, Takafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467656/
https://www.ncbi.nlm.nih.gov/pubmed/34576178
http://dx.doi.org/10.3390/ijms221810015