Synapsin-Promoted Caveolin-1 Overexpression Maintains Mitochondrial Morphology and Function in PSAPP Alzheimer’s Disease Mice

Mitochondrial dysfunction plays a pivotal role in the Alzheimer’s Disease (AD) pathology. Disrupted mitochondrial dynamics (i.e., fusion/fission balance), which are essential for normal mitochondria structure and function, are documented in AD. Caveolin-1 (Cav-1), a membrane/lipid raft (MLR) scaffol...

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Detalles Bibliográficos
Autores principales: Wang, Shanshan, Ichinomiya, Taiga, Terada, Yuki, Wang, Dongsheng, Patel, Hemal H., Head, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467690/
https://www.ncbi.nlm.nih.gov/pubmed/34572135
http://dx.doi.org/10.3390/cells10092487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467690/
https://www.ncbi.nlm.nih.gov/pubmed/34572135
http://dx.doi.org/10.3390/cells10092487

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