Differential Effects of Polyphenols on Insulin Proteolysis by the Insulin-Degrading Enzyme

The insulin-degrading enzyme (IDE) possesses a strong ability to degrade insulin and Aβ42 that has been linked to the neurodegeneration in Alzheimer’s disease (AD). Given this, an attractive IDE-centric strategy for the development of therapeutics for AD is to boost IDE’s activity for the clearance...

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Detalles Bibliográficos
Autores principales: Zheng, Qiuchen, Kebede, Micheal T., Lee, Bethany, Krasinski, Claire A., Islam, Saadman, Wurfl, Liliana A., Kemeh, Merc M., Ivancic, Valerie A., Jakobsche, Charles E., Spratt, Donald E., Lazo, Noel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467823/
https://www.ncbi.nlm.nih.gov/pubmed/34572974
http://dx.doi.org/10.3390/antiox10091342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467823/
https://www.ncbi.nlm.nih.gov/pubmed/34572974
http://dx.doi.org/10.3390/antiox10091342

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