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Significance of NPM1 Gene Mutations in AML

The aim of this literature review is to examine the significance of the nucleophosmin 1 (NPM1) gene in acute myeloid leukaemia (AML). This will include analysis of the structure and normal cellular function of NPM1, the type of mutations commonly witnessed in NPM1, and the mechanism by which this in...

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Detalles Bibliográficos
Autores principales: Hindley, Andrew, Catherwood, Mark Alexander, McMullin, Mary Frances, Mills, Ken I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467861/
https://www.ncbi.nlm.nih.gov/pubmed/34576201
http://dx.doi.org/10.3390/ijms221810040