Metformin and Dichloroacetate Suppress Proliferation of Liver Cancer Cells by Inhibiting mTOR Complex 1

The Warburg effect is important for cancer cell proliferation. This phenomenon can be flexible by interaction between glycolysis and mitochondrial oxidation for energy production. We aimed to investigate the anticancer effects of the pyruvate dehydrogenase kinase inhibitor, dichloroacetate (DCA) and...

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Detalles Bibliográficos
Autores principales: Kim, Tae Suk, Lee, Minjong, Park, Minji, Kim, Sae Yun, Shim, Min Suk, Lee, Chea Yeon, Choi, Dae Hee, Cho, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467948/
https://www.ncbi.nlm.nih.gov/pubmed/34576192
http://dx.doi.org/10.3390/ijms221810027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467948/
https://www.ncbi.nlm.nih.gov/pubmed/34576192
http://dx.doi.org/10.3390/ijms221810027

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