Association of Caspase 3 Activation and H2AX γ Phosphorylation in the Aging Brain: Studies on Untreated and Irradiated Mice

Phosphorylation of H2AX is a response to DNA damage, but γH2AX also associates with mitosis and/or apoptosis. We examined the effects of X-rays on DNA integrity to shed more light on the significance of H2AX phosphorylation and its relationship with activation of caspase 3 (CASP3), the main apoptoti...

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Detalles Bibliográficos
Autores principales: Gionchiglia, Nadia, Granato, Alberto, Merighi, Adalberto, Lossi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468010/
https://www.ncbi.nlm.nih.gov/pubmed/34572352
http://dx.doi.org/10.3390/biomedicines9091166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468010/
https://www.ncbi.nlm.nih.gov/pubmed/34572352
http://dx.doi.org/10.3390/biomedicines9091166

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