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Development of New Meridianin/Leucettine-Derived Hybrid Small Molecules as Nanomolar Multi-Kinase Inhibitors with Antitumor Activity

Although the sea ecosystem offers a broad range of bioactivities including anticancer, none of the FDA-approved antiproliferative protein kinase inhibitors are derived from a marine source. In a step to develop new marine-inspired potent kinase inhibitors with antiproliferative activities, a new ser...

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Detalles Bibliográficos
Autores principales: Elsherbeny, Mohamed H., Elkamhawy, Ahmed, Nada, Hossam, Abdellattif, Magda H., Lee, Kyeong, Roh, Eun Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468039/
https://www.ncbi.nlm.nih.gov/pubmed/34572319
http://dx.doi.org/10.3390/biomedicines9091131