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Development of New Meridianin/Leucettine-Derived Hybrid Small Molecules as Nanomolar Multi-Kinase Inhibitors with Antitumor Activity
Although the sea ecosystem offers a broad range of bioactivities including anticancer, none of the FDA-approved antiproliferative protein kinase inhibitors are derived from a marine source. In a step to develop new marine-inspired potent kinase inhibitors with antiproliferative activities, a new ser...
Autores principales: | Elsherbeny, Mohamed H., Elkamhawy, Ahmed, Nada, Hossam, Abdellattif, Magda H., Lee, Kyeong, Roh, Eun Joo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468039/ https://www.ncbi.nlm.nih.gov/pubmed/34572319 http://dx.doi.org/10.3390/biomedicines9091131 |
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