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Local Interleukin-12 Treatment Enhances the Efficacy of Radiation Therapy by Overcoming Radiation-Induced Immune Suppression

Radiation therapy (RT) recruits myeloid cells, leading to an immunosuppressive microenvironment that impedes its efficacy against tumors. Combination of immunotherapy with RT is a potential approach to reversing the immunosuppressive condition and enhancing tumor control after RT. This study aimed t...

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Detalles Bibliográficos
Autores principales: Yu, Ching-Fang, Chang, Chun-Hsiang, Wang, Chun-Chieh, Hong, Ji-Hong, Chiang, Chi-Shiun, Chen, Fang-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468040/
https://www.ncbi.nlm.nih.gov/pubmed/34576217
http://dx.doi.org/10.3390/ijms221810053