GPR30 Activation by 17β-Estradiol Promotes p62 Phosphorylation and Increases Estrogen Receptor α Protein Expression by Inducing Its Release from a Complex Formed with KEAP1

Estrogens can elicit rapid cellular responses via the G-protein-coupled receptor 30 (GPR30), followed by estrogen receptor α (ERα/ESR1)-mediated genomic effects. Here, we investigated whether rapid estrogen signaling via GRP30 may affect ESR1 expression, and we examined the underlying molecular mech...

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Detalles Bibliográficos
Autores principales: Tsai, Chia-Lung, Lin, Chiao-Yun, Chao, Angel, Lee, Yun-Shien, Wu, Ren-Chin, Tsai, Chi-Neu, Yen, Chih-Feng, Chao, An-Shine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468056/
https://www.ncbi.nlm.nih.gov/pubmed/34575683
http://dx.doi.org/10.3390/jpm11090906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468056/
https://www.ncbi.nlm.nih.gov/pubmed/34575683
http://dx.doi.org/10.3390/jpm11090906

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