Antioxidants Threaten Multikinase Inhibitor Efficacy against Liver Cancer by Blocking Mitochondrial Reactive Oxygen Species

Sorafenib and regorafenib, multikinase inhibitors (MKIs) used as standard chemotherapeutic agents for hepatocellular carcinoma (HCC), generate reactive oxygen species (ROS) during cancer treatment. Antioxidant supplements are becoming popular additions to our diet, particularly glutathione derivativ...

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Detalles Bibliográficos
Autores principales: Cucarull, Blanca, Tutusaus, Anna, Hernáez-Alsina, Tania, García de Frutos, Pablo, Reig, María, Colell, Anna, Marí, Montserrat, Morales, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468105/
https://www.ncbi.nlm.nih.gov/pubmed/34572967
http://dx.doi.org/10.3390/antiox10091336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468105/
https://www.ncbi.nlm.nih.gov/pubmed/34572967
http://dx.doi.org/10.3390/antiox10091336

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