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Protein–Protein Interactions in Translesion Synthesis

Translesion synthesis (TLS) is an error-prone DNA damage tolerance mechanism used by actively replicating cells to copy past DNA lesions and extend the primer strand. TLS ensures that cells continue replication in the presence of damaged DNA bases, albeit at the expense of an increased mutation rate...

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Detalles Bibliográficos
Autores principales: Dash, Radha Charan, Hadden, Kyle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468184/
https://www.ncbi.nlm.nih.gov/pubmed/34577015
http://dx.doi.org/10.3390/molecules26185544