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An Insulin-like Growth Factor-1 Conjugated Bombyx mori Silk Fibroin Film for Diabetic Wound Healing: Fabrication, Physicochemical Property Characterization, and Dosage Optimization In Vitro and In Vivo

This study aimed to develop a silk fibroin (SF)-film for the treatment of chronic diabetic wounds. Silk fibroin was purified through a newly developed heating degumming (HD) process and casted on a hydrophobic surface to form SF-films. The process allowed the fabricated film to achieve a 42% increas...

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Detalles Bibliográficos
Autores principales: Lin, Meng-Jin, Lu, Mei-Chun, Chan, Yun-Chen, Huang, Yu-Fen, Chang, Hwan-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468198/
https://www.ncbi.nlm.nih.gov/pubmed/34575535
http://dx.doi.org/10.3390/pharmaceutics13091459