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Tackling Stereochemistry in Drug Molecules with Vibrational Optical Activity

Chirality plays a crucial role in drug discovery and development. As a result, a significant number of commercially available drugs are structurally dissymmetric and enantiomerically pure. The determination of the exact 3D structure of drug candidates is, consequently, of paramount importance for th...

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Detalles Bibliográficos
Autores principales: Bogaerts, Jonathan, Aerts, Roy, Vermeyen, Tom, Johannessen, Christian, Herrebout, Wouter, Batista, Joao M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468215/
https://www.ncbi.nlm.nih.gov/pubmed/34577577
http://dx.doi.org/10.3390/ph14090877