Cargando…

Dynamic Crosstalk between Vascular Smooth Muscle Cells and the Aged Extracellular Matrix

Vascular aging is accompanied by the fragmentation of elastic fibers and collagen deposition, leading to reduced distensibility and increased vascular stiffness. A rigid artery facilitates elastin to degradation by MMPs, exposing vascular cells to greater mechanical stress and triggering signaling m...

Descripción completa

Detalles Bibliográficos
Autores principales: Ribeiro-Silva, Joao Carlos, Nolasco, Patricia, Krieger, Jose Eduardo, Miyakawa, Ayumi Aurea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468233/
https://www.ncbi.nlm.nih.gov/pubmed/34576337
http://dx.doi.org/10.3390/ijms221810175