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Dynamic Crosstalk between Vascular Smooth Muscle Cells and the Aged Extracellular Matrix
Vascular aging is accompanied by the fragmentation of elastic fibers and collagen deposition, leading to reduced distensibility and increased vascular stiffness. A rigid artery facilitates elastin to degradation by MMPs, exposing vascular cells to greater mechanical stress and triggering signaling m...
Autores principales: | Ribeiro-Silva, Joao Carlos, Nolasco, Patricia, Krieger, Jose Eduardo, Miyakawa, Ayumi Aurea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468233/ https://www.ncbi.nlm.nih.gov/pubmed/34576337 http://dx.doi.org/10.3390/ijms221810175 |
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