Inhibitors of Lipoxygenase and Cyclooxygenase-2 Attenuate Trimethyltin-Induced Neurotoxicity through Regulating Oxidative Stress and Pro-Inflammatory Cytokines in Human Neuroblastoma SH-SY5Y Cells

Trimethyltin (TMT) is an environmental neurotoxin that mediates dopaminergic neuronal injury in the brain. In this study, we characterized the toxic mechanism and possible protective compounds against TMT-induced neurotoxicity in human dopaminergic neuroblastoma SH-SY5Y cells. Antioxidants such as m...

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Detalles Bibliográficos
Autores principales: Song, Woo-Ju, Yun, Jang-Hyuk, Jeong, Myeong-Seon, Kim, Kil-Nam, Shin, Taekyun, Kim, Hyoung-Chun, Wie, Myung-Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468241/
https://www.ncbi.nlm.nih.gov/pubmed/34573138
http://dx.doi.org/10.3390/brainsci11091116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468241/
https://www.ncbi.nlm.nih.gov/pubmed/34573138
http://dx.doi.org/10.3390/brainsci11091116

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