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Inhibitors of Lipoxygenase and Cyclooxygenase-2 Attenuate Trimethyltin-Induced Neurotoxicity through Regulating Oxidative Stress and Pro-Inflammatory Cytokines in Human Neuroblastoma SH-SY5Y Cells
Trimethyltin (TMT) is an environmental neurotoxin that mediates dopaminergic neuronal injury in the brain. In this study, we characterized the toxic mechanism and possible protective compounds against TMT-induced neurotoxicity in human dopaminergic neuroblastoma SH-SY5Y cells. Antioxidants such as m...
Autores principales: | Song, Woo-Ju, Yun, Jang-Hyuk, Jeong, Myeong-Seon, Kim, Kil-Nam, Shin, Taekyun, Kim, Hyoung-Chun, Wie, Myung-Bok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468241/ https://www.ncbi.nlm.nih.gov/pubmed/34573138 http://dx.doi.org/10.3390/brainsci11091116 |
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