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Alpha-Ketoglutarate: A Potential Inner Mitochondrial and Cytosolic Protector against Peroxynitrite and Peroxynitrite-Induced Nitration?

The generation of peroxynitrite (ONOO(−)) is associated with several diseases, including atherosclerosis, hypertension, neurodegeneration, cancer, inflammation, and sepsis. Alpha-ketoglutarate (αKG) is a known potential highly antioxidative agent for radical oxidative species such as peroxides. The...

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Detalles Bibliográficos
Autores principales: Greilberger, Joachim, Greilberger, Michaela, Wintersteiger, Reinhold, Zangger, Klaus, Herwig, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468307/
https://www.ncbi.nlm.nih.gov/pubmed/34573133
http://dx.doi.org/10.3390/antiox10091501