Oxazinethione Derivatives as a Precursor to Pyrazolone and Pyrimidine Derivatives: Synthesis, Biological Activities, Molecular Modeling, ADME, and Molecular Dynamics Studies

In this study, we used oxazinethione as a perfect precursor to synthesize new pyrimidine and pyrazole derivatives with potent biological activities. Biological activities were determined for all compounds against A. flavus, E. coli, S. aureus, and F. moniliform. Compounds 3, 4a-b, and 5 exhibited hi...

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Detalles Bibliográficos
Autores principales: Abdellattif, Magda H., Shahbaaz, Mohd, Arief, M. M. H., Hussien, Mostafa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468439/
https://www.ncbi.nlm.nih.gov/pubmed/34576953
http://dx.doi.org/10.3390/molecules26185482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468439/
https://www.ncbi.nlm.nih.gov/pubmed/34576953
http://dx.doi.org/10.3390/molecules26185482

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