p47(phox)-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis

The p47(phox) is a key regulatory subunit of Nox2-containing NADPH oxidase (Nox2) that by generating reactive oxygen species (ROS) plays an important role in Angiotensin II (AngII)-induced cardiac hypertrophy and heart failure. However, the signalling pathways of p47(phox) in the heart remains uncle...

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Detalles Bibliográficos
Autores principales: Liu, Fangfei, Fan, Lampson M., Geng, Li, Li, Jian-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468498/
https://www.ncbi.nlm.nih.gov/pubmed/34572995
http://dx.doi.org/10.3390/antiox10091363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468498/
https://www.ncbi.nlm.nih.gov/pubmed/34572995
http://dx.doi.org/10.3390/antiox10091363

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