Environmental Enrichment Rescues Social Behavioral Deficits and Synaptic Abnormalities in Pten Haploinsufficient Mice

Pten germline haploinsufficient (Pten(+/−)) mice, which model macrocephaly/autism syndrome, show social and repetitive behavior deficits, early brain overgrowth, and cortical–subcortical hyperconnectivity. Previous work indicated that altered neuronal connectivity may be a substrate for behavioral d...

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Detalles Bibliográficos
Autores principales: Clipperton-Allen, Amy E., Zhang, Angela, Cohen, Ori S., Page, Damon Theron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468545/
https://www.ncbi.nlm.nih.gov/pubmed/34573348
http://dx.doi.org/10.3390/genes12091366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468545/
https://www.ncbi.nlm.nih.gov/pubmed/34573348
http://dx.doi.org/10.3390/genes12091366

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