Glomerular Mesangial Cell pH Homeostasis Mediates Mineralocorticoid Receptor-Induced Cell Proliferation

Mineralocorticoids (e.g., aldosterone) support chronic inflammatory tissue damage, including glomerular mesangial injury leading to glomerulosclerosis. Furthermore, aldosterone leads to activation of the extracellular signal-regulated kinases (ERK1/2) in rat glomerular mesangial cells (GMC). Because...

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Detalles Bibliográficos
Autores principales: Gekle, Michael, Mildenberger, Sigrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468551/
https://www.ncbi.nlm.nih.gov/pubmed/34572303
http://dx.doi.org/10.3390/biomedicines9091117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468551/
https://www.ncbi.nlm.nih.gov/pubmed/34572303
http://dx.doi.org/10.3390/biomedicines9091117

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