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Quest for the Molecular Basis of Improved Selective Toxicity of All-Trans Isomers of Aromatic Heptaene Macrolide Antifungal Antibiotics

Three aromatic heptaene macrolide antifungal antibiotics, Candicidin D, Partricin A (Gedamycin) and Partricin B (Vacidin) were subjected to controlled cis-trans → all trans photochemical isomerization. The obtained all-trans isomers demonstrated substantially improved in vitro selective toxicity in...

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Detalles Bibliográficos
Autores principales:	Borzyszkowska-Bukowska, Julia, Górska, Justyna, Szczeblewski, Paweł, Laskowski, Tomasz, Gabriel, Iwona, Jurasz, Jakub, Kozłowska-Tylingo, Katarzyna, Szweda, Piotr, Milewski, Sławomir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468583/ https://www.ncbi.nlm.nih.gov/pubmed/34576271 http://dx.doi.org/10.3390/ijms221810108

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