Cellular Plasticity: A Route to Senescence Exit and Tumorigenesis

SIMPLE SUMMARY: Senescence is a form of cell cycle arrest induced by stresses such as DNA damage and oncogenes and therefore constitutes a crucial barrier against cancer. Nevertheless, senescent cells can escape or bypass this tumor suppressor mechanism and evolve towards an altered, pre-cancerous g...

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Detalles Bibliográficos
Autores principales: De Blander, Hadrien, Morel, Anne-Pierre, Senaratne, Aruni P., Ouzounova, Maria, Puisieux, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468602/
https://www.ncbi.nlm.nih.gov/pubmed/34572787
http://dx.doi.org/10.3390/cancers13184561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468602/
https://www.ncbi.nlm.nih.gov/pubmed/34572787
http://dx.doi.org/10.3390/cancers13184561

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