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Cellular Plasticity: A Route to Senescence Exit and Tumorigenesis

SIMPLE SUMMARY: Senescence is a form of cell cycle arrest induced by stresses such as DNA damage and oncogenes and therefore constitutes a crucial barrier against cancer. Nevertheless, senescent cells can escape or bypass this tumor suppressor mechanism and evolve towards an altered, pre-cancerous g...

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Detalles Bibliográficos
Autores principales:	De Blander, Hadrien, Morel, Anne-Pierre, Senaratne, Aruni P., Ouzounova, Maria, Puisieux, Alain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468602/ https://www.ncbi.nlm.nih.gov/pubmed/34572787 http://dx.doi.org/10.3390/cancers13184561

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