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A Systematic Comparison of Antiandrogens Identifies Androgen Receptor Protein Stability as an Indicator for Treatment Response

Antiandrogen therapy is a primary treatment for patients with metastasized prostate cancer. Whilst the biologic mechanisms of antiandrogens have been extensively studied, the operating protocols used for the characterization of these drugs were not identical, limiting their comparison. Here, the ant...

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Detalles Bibliográficos
Autores principales: Siciliano, Tiziana, Simons, Ingo H., Beier, Alicia-Marie K., Ebersbach, Celina, Aksoy, Cem, Seed, Robert I., Stope, Matthias B., Thomas, Christian, Erb, Holger H. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468615/
https://www.ncbi.nlm.nih.gov/pubmed/34575023
http://dx.doi.org/10.3390/life11090874