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Engineering a Vascularized Hypoxic Tumor Model for Therapeutic Assessment

Solid tumors in advanced cancer often feature a structurally and functionally abnormal vasculature through tumor angiogenesis, which contributes to cancer progression, metastasis, and therapeutic resistances. Hypoxia is considered a major driver of angiogenesis in tumor microenvironments. However, t...

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Detalles Bibliográficos
Autores principales: Ando, Yuta, Oh, Jeong Min, Zhao, Winfield, Tran, Madeleine, Shen, Keyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468635/
https://www.ncbi.nlm.nih.gov/pubmed/34571851
http://dx.doi.org/10.3390/cells10092201