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Cytotoxic Marine Alkaloid 3,10-Dibromofascaplysin Induces Apoptosis and Synergizes with Cytarabine Resulting in Leukemia Cell Death

Myeloid leukemia is a hematologic neoplasia characterized by a clonal proliferation of hematopoietic stem cell progenitors. Patient prognosis varies depending on the subtype of leukemia as well as eligibility for intensive treatment regimens and allogeneic stem cell transplantation. Although signifi...

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Detalles Bibliográficos
Autores principales: Spirin, Pavel, Shyrokova, Elena, Lebedev, Timofey, Vagapova, Elmira, Smirnova, Polina, Kantemirov, Alexey, Dyshlovoy, Sergey A., von Amsberg, Gunhild, Zhidkov, Maxim, Prassolov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468638/
https://www.ncbi.nlm.nih.gov/pubmed/34564151
http://dx.doi.org/10.3390/md19090489