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In Silico Study, Physicochemical, and In Vitro Lipase Inhibitory Activity of α,β-Amyrenone Inclusion Complexes with Cyclodextrins

α,β-amyrenone (ABAME) is a triterpene derivative with many biological activities; however, its potential pharmacological use is hindered by its low solubility in water. In this context, the present work aimed to develop inclusion complexes (ICs) of ABAME with γ- and β-cyclodextrins (CD), which were...

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Detalles Bibliográficos
Autores principales: de Oliveira, Luana Carvalho, de Menezes, Danielle Lima Bezerra, da Silva, Valéria Costa, Lourenço, Estela Mariana Guimarães, Miranda, Paulo Henrique Santana, da Silva, Márcia de Jesus Amazonas, Lima, Emerson Silva, Júnior, Valdir Florêncio da Veiga, Marreto, Ricardo Neves, Converti, Attilio, Barbosa, Euzébio Guimaraes, de Lima, Ádley Antonini Neves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468659/
https://www.ncbi.nlm.nih.gov/pubmed/34576044
http://dx.doi.org/10.3390/ijms22189882