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In Silico Study, Physicochemical, and In Vitro Lipase Inhibitory Activity of α,β-Amyrenone Inclusion Complexes with Cyclodextrins
α,β-amyrenone (ABAME) is a triterpene derivative with many biological activities; however, its potential pharmacological use is hindered by its low solubility in water. In this context, the present work aimed to develop inclusion complexes (ICs) of ABAME with γ- and β-cyclodextrins (CD), which were...
Autores principales: | de Oliveira, Luana Carvalho, de Menezes, Danielle Lima Bezerra, da Silva, Valéria Costa, Lourenço, Estela Mariana Guimarães, Miranda, Paulo Henrique Santana, da Silva, Márcia de Jesus Amazonas, Lima, Emerson Silva, Júnior, Valdir Florêncio da Veiga, Marreto, Ricardo Neves, Converti, Attilio, Barbosa, Euzébio Guimaraes, de Lima, Ádley Antonini Neves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468659/ https://www.ncbi.nlm.nih.gov/pubmed/34576044 http://dx.doi.org/10.3390/ijms22189882 |
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