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Mitochondrial Disruption by Amyloid Beta 42 Identified by Proteomics and Pathway Mapping

Alzheimer’s disease (AD) is marked by chronic neurodegeneration associated with the occurrence of plaques containing amyloid β (Aβ) proteins in various parts of the human brain. An increase in several Aβ fragments is well documented in patients with AD and anti-amyloid targeting is an emerging area...

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Detalles Bibliográficos
Autores principales: Sinclair, Patricia, Baranova, Ancha, Kabbani, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468661/
https://www.ncbi.nlm.nih.gov/pubmed/34572029
http://dx.doi.org/10.3390/cells10092380