α-Synuclein Decreases the Abundance of Proteasome Subunits and Alters Ubiquitin Conjugates in Yeast

Parkinson’s disease (PD) is the most prevalent movement disorder characterized with loss of dopaminergic neurons in the brain. One of the pathological hallmarks of the disease is accumulation of aggregated α-synuclein (αSyn) in cytoplasmic Lewy body inclusions that indicates significant dysfunction...

Descripción completa

Detalles Bibliográficos
Autores principales: Popova, Blagovesta, Galka, Dajana, Häffner, Nicola, Wang, Dan, Schmitt, Kerstin, Valerius, Oliver, Knop, Michael, Braus, Gerhard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468666/
https://www.ncbi.nlm.nih.gov/pubmed/34571878
http://dx.doi.org/10.3390/cells10092229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468666/
https://www.ncbi.nlm.nih.gov/pubmed/34571878
http://dx.doi.org/10.3390/cells10092229

Ejemplares similares