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α-Synuclein Decreases the Abundance of Proteasome Subunits and Alters Ubiquitin Conjugates in Yeast
Parkinson’s disease (PD) is the most prevalent movement disorder characterized with loss of dopaminergic neurons in the brain. One of the pathological hallmarks of the disease is accumulation of aggregated α-synuclein (αSyn) in cytoplasmic Lewy body inclusions that indicates significant dysfunction...
Autores principales: | Popova, Blagovesta, Galka, Dajana, Häffner, Nicola, Wang, Dan, Schmitt, Kerstin, Valerius, Oliver, Knop, Michael, Braus, Gerhard H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468666/ https://www.ncbi.nlm.nih.gov/pubmed/34571878 http://dx.doi.org/10.3390/cells10092229 |
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