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4-Hydroxyderricin Promotes Apoptosis and Cell Cycle Arrest through Regulating PI3K/AKT/mTOR Pathway in Hepatocellular Cells

4-hydroxyderricin (4-HD), as a natural flavonoid compound derived from Angelica keiskei, has largely unknown inhibition and mechanisms on liver cancer. Herein, we investigated the inhibitory effects of 4-HD on hepatocellular carcinoma (HCC) cells and clarified the potential mechanisms by exploring a...

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Detalles Bibliográficos
Autores principales: Gao, Xiang, Jiang, Yuhuan, Xu, Qi, Liu, Feng, Pang, Xuening, Wang, Mingji, Li, Qun, Li, Zichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468691/
https://www.ncbi.nlm.nih.gov/pubmed/34574146
http://dx.doi.org/10.3390/foods10092036