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Exploring EZH2-Proteasome Dual-Targeting Drug Discovery through a Computational Strategy to Fight Multiple Myeloma

Multiple myeloma is an incurable plasma cell neoplastic disease representing about 10–15% of all haematological malignancies diagnosed in developed countries. Proteasome is a key player in multiple myeloma and proteasome inhibitors are the current first-line of treatment. However, these are associat...

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Detalles Bibliográficos
Autores principales: Estrada, Filipe G. A., Miccoli, Silvia, Aniceto, Natália, García-Sosa, Alfonso T., Guedes, Rita C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468724/
https://www.ncbi.nlm.nih.gov/pubmed/34577052
http://dx.doi.org/10.3390/molecules26185574